Naglo A S, Nergårdh A, Boréus L O
Scand J Urol Nephrol. 1981;15(2):97-102. doi: 10.3109/00365598109179583.
Bladder hyperactivity defined as unconscious, involuntary detrusor contractions giving rise to intravesical pressure increase of at least 15 cm H2O and of minimum 15 sec duration, has been examined in 9 children with myelodysplasia and incontinence. The effect of atropine and isoprenaline on the hyperactivity pattern was evaluated. Atropine had a dose-related inhibiting influence on both frequency and amplitude of detrusor contractions whereas isoprenaline was without these favourable effects.
膀胱活动亢进被定义为无意识的、非自愿的逼尿肌收缩，导致膀胱内压升高至少15厘米水柱，持续时间至少15秒。我们对9名患有脊髓发育不良和尿失禁的儿童进行了检查，并评估了阿托品和异丙肾上腺素对这种活动亢进模式的影响。阿托品对逼尿肌收缩的频率和幅度具有剂量相关的抑制作用，而异丙肾上腺素则没有这些有益效果。
