原发性睡眠呼吸暂停综合征
Primary sleep apnoea syndrome.
作者信息
Chokroverty S, Sharp J T
出版信息
J Neurol Neurosurg Psychiatry. 1981 Nov;44(11):970-82. doi: 10.1136/jnnp.44.11.970.
Abstract
Polygraphic study in 18 men with the sleep apnoea syndrome showed central, upper airway obstructive, and mixed apnoeas. Fifty per cent of the total apnoea time was central, 33% was obstructive, and 17% was mixed. Apnoeic episodes were accompanied by oxygen desaturation, relative bradycardia and hypotonia of orofacial muscles innervated by ponto-medullary neurons. During regular breathing these muscles revealed tonic and phasic inspiratory EMG activities. The data suggest that the primary sleep apnoea syndrome results from a dysfunction of the central control of breathing.
摘要
对18名患有睡眠呼吸暂停综合征的男性进行的多导睡眠图研究显示，存在中枢性、上气道阻塞性和混合性呼吸暂停。中枢性呼吸暂停占总呼吸暂停时间的50%，阻塞性呼吸暂停占33%，混合性呼吸暂停占17%。呼吸暂停发作伴有氧饱和度下降、相对心动过缓和由脑桥延髓神经元支配的口面部肌肉张力减退。在正常呼吸期间，这些肌肉表现出紧张性和阶段性吸气肌电图活动。数据表明，原发性睡眠呼吸暂停综合征是由呼吸中枢控制功能障碍引起的。
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