Z Alternsforsch. 1981;36(5):409-15.
Studies have been carried out on the age-specific peculiarities of the distribution in the metabolic sphere of radioactive carbon-2-14C-glycine, on the intensity of its utilization in the synthesis of tissue and serum proteins, lipids and glycogen, and on the excretory level in the urine of radioactive products of metabolism in young and old animals adapted to portions of food containing different amount of protein. As has been shown, the intensity of the assimilation and dissimilation phases of the protein metabolism decreases with age. An increase in the protein content of the diet fed to old animals has no activating effect on the protein synthesis; it results in an increased utilization of the metabolic products in the biosynthesis of lipids, but not glycogen which fact is characteristic of an optical nutrient ratio. The consumption of foodstuffs influences both the state of health and the life-span of the organism. The literature contains a great many data on the unfavourable influence of various food ingredients on the organism (1-3). It has been pointed out in this context that age-related food and energy requirements play an important role also in the rational nutrition of the aged, and that an adequate limitation of the fat and carbohydrate content of the food rations of old people is not inconsistent with the above statement.
针对放射性碳-2(¹⁴C)-甘氨酸在代谢领域分布的年龄特异性特点、其在组织和血清蛋白、脂质及糖原合成中利用的强度,以及适应不同蛋白质含量食物的幼龄和老龄动物尿液中代谢放射性产物的排泄水平,开展了多项研究。结果表明,蛋白质代谢的同化和异化阶段强度随年龄增长而降低。给老龄动物喂食的日粮中蛋白质含量增加,对蛋白质合成没有激活作用;这会导致代谢产物在脂质生物合成中的利用率增加,但在糖原生物合成中并非如此,这一事实是适宜营养比例的特征。食物的消耗会影响机体的健康状况和寿命。文献中有大量关于各种食物成分对机体产生不利影响的数据(1 - 3)。在此背景下指出,与年龄相关的食物和能量需求在老年人合理营养中也起着重要作用,并且适当限制老年人食物定量中的脂肪和碳水化合物含量与上述观点并不矛盾。