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短暂性缺氧对耳蜗电位的影响。

The effect of transient anoxia upon the cochlear potentials.

作者信息

Kusakari J, Kambayashi J, Kobayashi T, Rokugo M, Arakawa E, Ohyama K, Kaneko Y

出版信息

Auris Nasus Larynx. 1981;8(2):55-64. doi: 10.1016/s0385-8146(81)80002-8.

Abstract

To contribute to the analysis of the electrocochleographical findings in humans, the reversibility of the cochlear potentials (the AP, CM, and SP) after transient anoxia was examined using 24 albino guinea pigs. The durations of anoxia ranged from 5 to 120 min, and the AP, CM and SP were examined one hour after restoration of the blood supply. The mildest form of cochlear damage after transient anoxia was the disappearance of the L-part of the AP and the severest was the complete abolition of these potentials. The severity of the damage closely correlated with the duration of anoxia. The AP was poorer in reversibility than the CM and the SP. These results were analysed and discussed in the light of literature on clinical and basic studies.

摘要

为了有助于对人类耳蜗电图检查结果进行分析,我们使用24只白化豚鼠研究了短暂缺氧后耳蜗电位(动作电位、复合动作电位和总和电位)的可逆性。缺氧持续时间为5至120分钟,恢复供血1小时后检测动作电位、复合动作电位和总和电位。短暂缺氧后耳蜗损伤最轻微的形式是动作电位L波消失,最严重的是这些电位完全消失。损伤的严重程度与缺氧持续时间密切相关。动作电位的可逆性比复合动作电位和总和电位差。我们根据临床和基础研究的文献对这些结果进行了分析和讨论。

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