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短暂性缺氧对耳蜗电位的影响。

The effect of transient anoxia upon the cochlear potentials.

作者信息

Kusakari J, Kambayashi J, Kobayashi T, Rokugo M, Arakawa E, Ohyama K, Kaneko Y

出版信息

Auris Nasus Larynx. 1981;8(2):55-64. doi: 10.1016/s0385-8146(81)80002-8.

DOI:10.1016/s0385-8146(81)80002-8
PMID:7337589
Abstract

To contribute to the analysis of the electrocochleographical findings in humans, the reversibility of the cochlear potentials (the AP, CM, and SP) after transient anoxia was examined using 24 albino guinea pigs. The durations of anoxia ranged from 5 to 120 min, and the AP, CM and SP were examined one hour after restoration of the blood supply. The mildest form of cochlear damage after transient anoxia was the disappearance of the L-part of the AP and the severest was the complete abolition of these potentials. The severity of the damage closely correlated with the duration of anoxia. The AP was poorer in reversibility than the CM and the SP. These results were analysed and discussed in the light of literature on clinical and basic studies.

摘要

为了有助于对人类耳蜗电图检查结果进行分析,我们使用24只白化豚鼠研究了短暂缺氧后耳蜗电位(动作电位、复合动作电位和总和电位)的可逆性。缺氧持续时间为5至120分钟,恢复供血1小时后检测动作电位、复合动作电位和总和电位。短暂缺氧后耳蜗损伤最轻微的形式是动作电位L波消失,最严重的是这些电位完全消失。损伤的严重程度与缺氧持续时间密切相关。动作电位的可逆性比复合动作电位和总和电位差。我们根据临床和基础研究的文献对这些结果进行了分析和讨论。

相似文献

1
The effect of transient anoxia upon the cochlear potentials.短暂性缺氧对耳蜗电位的影响。
Auris Nasus Larynx. 1981;8(2):55-64. doi: 10.1016/s0385-8146(81)80002-8.
2
[Functional and morphological changes of the cochlea in guinea pigs during anoxia].[缺氧期间豚鼠耳蜗的功能和形态学变化]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(5):265-7, 313.
3
The effect of mannitol upon cochlear dysfunction induced by transient local anoxia.甘露醇对短暂局部缺氧所致耳蜗功能障碍的影响。
Hear Res. 1998 Dec;126(1-2):28-36. doi: 10.1016/s0378-5955(98)00142-7.
4
A comparison of compound action potential and cochlear microphonic two-tone suppression in the guinea pig.豚鼠复合动作电位与耳蜗微音器电位双音抑制的比较
Hear Res. 1982 Sep;8(1):83-91. doi: 10.1016/0378-5955(82)90037-5.
5
[The changes in the summating potential and morphology in the cochlea of guinea pigs with anoxia].[缺氧豚鼠耳蜗中总和电位及形态学的变化]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1994;29(2):74-7.
6
Effect of 7-nitroindazole upon cochlear dysfunction induced by transient local anoxia.
Ann Otol Rhinol Laryngol. 2000 Aug;109(8 Pt 1):715-9. doi: 10.1177/000348940010900803.
7
Cochlear potentials of guinea pigs with experimentally induced renal failure.
Acta Otolaryngol Suppl. 1987;435:40-5. doi: 10.3109/00016488709107349.
8
Changes in cochlear oxygenation, microcirculation and auditory function during prolonged general hypoxia.长时间全身缺氧期间耳蜗氧合、微循环及听觉功能的变化
Eur Arch Otorhinolaryngol. 1993;250(7):396-400. doi: 10.1007/BF00180384.
9
Effect of nitric oxide synthase inhibitor on cochlear dysfunction induced by transient local anoxia.一氧化氮合酶抑制剂对短暂局部缺氧诱导的耳蜗功能障碍的影响。
Acta Otolaryngol. 1999 Mar;119(2):179-84. doi: 10.1080/00016489950181620.
10
The effect of vasopressin upon the cochlear potentials in the guinea pig.
Acta Otolaryngol. 1986 Mar-Apr;101(3-4):217-23. doi: 10.3109/00016488609132830.

引用本文的文献

1
The use of hyperbaric oxygen therapy in acute hearing loss: a narrative review.高压氧疗法在急性听力损失中的应用:叙述性综述。
Eur Arch Otorhinolaryngol. 2019 Jul;276(7):1859-1880. doi: 10.1007/s00405-019-05469-7. Epub 2019 May 20.
2
Observations of cochlear blood flow dynamics using the laser Doppler flowmeter.使用激光多普勒血流仪对耳蜗血流动力学进行观察。
Arch Otorhinolaryngol. 1989;246(3):147-50. doi: 10.1007/BF00456656.
3
Cochlear blood flow following temporary occlusion of the cerebellar arteries.小脑动脉暂时闭塞后的耳蜗血流量。
Eur Arch Otorhinolaryngol. 1990;247(4):226-8. doi: 10.1007/BF00178990.