Mortara P, Bardelli D, Leone M, Schiffer D
Ital J Neurol Sci. 1981 Aug;2(3):237-42. doi: 10.1007/BF02335403.
210 cases of ALS disease in the period 1955-1979 are considered. Different parameters such as sex, age, duration and clinical course have been correlated with four clinical types: conventional, pseudopolyneuritic, pyramidal and bulbar. The age distribution shows a peak in the fifth decade of life. The sex ratio is 2.08:1. Considering together all the clinical types, the mean duration of the disease is 27.05 months. The bulbar variety has the poorest prognosis (19.6 months) and the pyramidal variety the best (37.59 months). Familiarity is evidenced in only 3 cases. All our data are discussed and compared with those of the literature.
研究了1955年至1979年期间的210例肌萎缩侧索硬化症（ALS）病例。对性别、年龄、病程和临床过程等不同参数与四种临床类型进行了相关性分析，这四种临床类型分别为：传统型、假多神经炎型、锥体束型和延髓型。年龄分布在生命的第五个十年出现峰值。男女比例为(2.08:1)。综合所有临床类型来看，疾病的平均病程为27.05个月。延髓型预后最差（19.6个月），锥体束型预后最好（37.59个月）。仅3例有家族病史。对我们所有的数据进行了讨论，并与文献中的数据进行了比较。
