Jokelainen M
J Neurol Sci. 1976 Sep;29(1):55-63. doi: 10.1016/0022-510x(76)90080-0.
The mortality and prevalence of ALS in the various countries of Finland was studied. The work was based on death certificates derived from a 10-year period from 1963 to 1972, and altogether 421 cases were found. The mean duration of the disease was 2.7 years, and the mean age at death was 61.2 years. The average annual mortality rate was 0.91 per 100,000. The male to female ratio was 0.87 to 1, males outnumbered females only in age groups under 65. Some clustering of the cases seems to be taking place in the south-eastern part of the country. The rural to urban distribution of the patients' places of birth and domiciles did not differ markedly from that of thw whole population. After ALS itself pneumonia was the most common direct cause of death. Of other significant conditions coded in the death certificates schizophrenia and cancer did not occur more often than could be expected by chance. No evidence of inheritance of the disease was found.
对芬兰各个国家肌萎缩侧索硬化症（ALS）的死亡率和患病率进行了研究。这项工作基于1963年至1972年这10年间的死亡证明，共发现421例病例。疾病的平均病程为2.7年，平均死亡年龄为61.2岁。年平均死亡率为每10万人0.91例。男女比例为0.87比1，仅在65岁以下年龄组男性人数超过女性。病例似乎在该国东南部出现了一些聚集现象。患者出生地和住所的城乡分布与整个人口的分布没有明显差异。除ALS本身外，肺炎是最常见的直接死因。在死亡证明中编码的其他重要病症中，精神分裂症和癌症的发生频率并未高于偶然预期。未发现该疾病有遗传证据。
