Banquet J P, Renault B, Lesèvre N
Biol Psychol. 1981 Dec;13:203-14. doi: 10.1016/0301-0511(81)90036-3.
Some experimental data demonstrate the existence of at least two different P300s distinguished by latency, topography and functional significance. These positive waves are preceded by a negative component which has been labelled N200. The purpose of this study was to analyze the modifications of these negative and positive components according to probability and task (GO vs. NOGO) in order to better understand the significance of each of them in terms of stages of information processing. Six normal subjects were tested twice on separate days, in a GO-NOGO paradigm. Auditory stimuli - high pitch (GO) and low pitch (NOGO) - were presented in three different occurrence probability combinations: 0.2/0.8; 0.5/0.5; 0.8/0.2, in successive blocks. In both GO and NOGO responses, a vertex N200 component was followed by two positive waves - the first peaking at 300 msec at Cz (Cz : P300), the other one Ca 400 msec at Pz (Pz : P400). An inverse relation between amplitude and probability was seen for the three components but it was twice as large for P400 as for P300. A task effect was only seen for N200, the amplitude and latency of which increased in the GO condition. From the first session to the second, the amplitude of N200 decreased whereas that of P300 increased.
一些实验数据表明，至少存在两种不同的P300，可通过潜伏期、地形图和功能意义加以区分。这些正波之前有一个负成分，被标记为N200。本研究的目的是根据概率和任务（执行与不执行）分析这些负成分和正成分的变化，以便从信息处理阶段更好地理解它们各自的意义。六名正常受试者在不同日期分两次接受执行-不执行范式测试。听觉刺激——高音（执行）和低音（不执行）——以三种不同的出现概率组合呈现：0.2/0.8；0.5/0.5；0.8/0.2，依次进行。在执行和不执行反应中，头顶的N200成分之后都有两个正波——第一个在Cz处300毫秒达到峰值（Cz：P300），另一个在Pz处400毫秒达到峰值（Pz：P400）。这三个成分的振幅与概率呈反比关系，但P400的反比关系是P300的两倍。仅在N200上观察到任务效应，其振幅和潜伏期在执行条件下增加。从第一次测试到第二次测试，N200的振幅下降，而P300的振幅增加。
