Steinau H U, Elert O, Schneider M
Handchirurgie. 1981;13(1-2):149-51.
An experimental study about post-ischemic perfusion of muscles with a new stroma-free hemoglobin solution is presented. Compared to other storage and perfusion methods the solution has several advantages: 1. Oxygenation and metabolism of the skeletal muscles are preserved. 2. Excellent wash-out effect. 3. The rheologic characteristics are better than those of whole blood. 4. No incompatibility. 5. No thrombogenetic effect. 6. The method is easy to manage. Our ultrastructural investigations show less damage of the muscle cells after a post-ischemic perfusion with oxygenated hemoglobin solution than after a post-ischemic physiological perfusion with whole blood.
本文介绍了一项关于用一种新型无基质血红蛋白溶液对缺血后肌肉进行灌注的实验研究。与其他储存和灌注方法相比，该溶液具有以下几个优点：1. 骨骼肌的氧合和代谢得以保留。2. 具有出色的洗脱效果。3. 流变学特性优于全血。4. 无不相容性。5. 无血栓形成作用。6. 该方法易于操作。我们的超微结构研究表明，与用全血进行缺血后生理灌注相比，用含氧血红蛋白溶液进行缺血后灌注对肌肉细胞的损伤更小。
