Sinn W
Z Gesamte Inn Med. 1981 Sep 1;36(17):602-7.
By epicutaneous skin test by means of 1-monochlorine-2,4-dinitrobenzene (DNCB) the primary cell-conditioned immunity is induced and is provable by the allergic skin reaction of late type. The examination of 125 clinically healthy persons of either sex at the age of 17-57 years confirms the suitability of self-produced, welded into foil skin test plasters layered with DNCB in various stages of concentration for clinical use. A 48-hour skin contact with 0.049 molar DNCB-solution (1,000 microgram DNCB: 100 microliter Ol. oliv.) leads to a late reaction in 84% of the cases, in the repeated case in 98% of the cases. The valuation of the eczema-typical symptoms is suitable for the characterization and quantification. There were no differences in age and sex. Ultrastrong reactions were not registered.
通过使用1-氯-2,4-二硝基苯(DNCB)进行表皮皮肤试验,可诱导原发性细胞条件免疫,并可通过迟发型过敏皮肤反应得到证实。对125名年龄在17至57岁之间的临床健康男女进行的检查证实,自行制作的、焊接在箔片上并分层含有不同浓度DNCB的皮肤试验贴剂适用于临床使用。与0.049摩尔DNCB溶液(1000微克DNCB:100微升橄榄油)进行48小时皮肤接触,84%的病例会出现迟发反应,重复试验时98%的病例会出现迟发反应。对湿疹典型症状的评估适用于特征描述和量化。在年龄和性别方面没有差异。未记录到超强反应。