Sabioncello A, Rabatic S, Kadrnka-Lovrencic M, Oberiter V, Dekaris D
Biomedicine. 1981 Dec;35(7-8):227-9.
Leucocyte-mediated phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) were tested in 48 children with type-1 diabetes and in 22 healthy children. Both phagocytosis and ADCC for opsonized 51Cr-erythrocytes significantly decreased in the diabetics. Phagocytosis decreased in well and in poorly balanced diabetics, but the latter, having type-1 diabetes for less than 5 years, exhibited a lower phagocytic capacity than the patients with a longer duration of disease. The decrease of ADCC in poorly balanced patients was greater than in the well balanced ones as compared to the controls. The duration of diabetes was without influence on their leucocytes' ADCC.
在48名1型糖尿病患儿和22名健康儿童中检测了白细胞介导的吞噬作用和抗体依赖性细胞毒性（ADCC）。糖尿病患儿对调理过的51Cr标记红细胞的吞噬作用和ADCC均显著降低。病情稳定和不稳定的糖尿病患儿吞噬作用均降低，但后者患1型糖尿病不到5年，其吞噬能力低于病程较长的患者。与对照组相比，病情不稳定患者的ADCC下降幅度大于病情稳定患者。糖尿病病程对其白细胞的ADCC没有影响。
