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Function of granulocytes in B-chronic lymphatic leukaemia.

作者信息

Dekaris D, Handl S, Sabioncello A, Rabatić S

机构信息

Institute of Immunology, University of Zagreb, Yugoslavia.

出版信息

Blut. 1990 Dec;61(6):354-7. doi: 10.1007/BF01738549.

DOI:10.1007/BF01738549
PMID:2291983
Abstract

To study the function of granulocytes in patients with B-cell chronic lymphatic leukaemia (B-CLL), granulocytes were separated from peripheral blood of 48 patients (mean age: 69 years) and 35 apparently healthy age-matched volunteers. Spontaneous mobility, ingestion, digestion and antibody dependent cellular cytotoxicity (ADCC) of granulocytes were assessed. Decreased spontaneous mobility was found in granulocytes from patients with B-CLL but between the two groups no detectable differences were encountered in the other parameters tested. No alterations of granulocytes functions were found to be correlated with clinical stages of B-CLL. If granulocytes functions were compared in treated (chlorambucil, steroids) and untreated patients, a significant decrease in digestion was found in treated patients.

摘要

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本文引用的文献

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THE ROLE OF THE PHAGOCYTE IN HOST-PARASITE INTERACTIONS. I. THE PHAGOCYTIC CAPABILITIES OF LEUKOCYTES FROM LYMPHOPROLIFERATIVE DISORDERS.吞噬细胞在宿主-寄生虫相互作用中的作用。I. 淋巴增生性疾病中白细胞的吞噬能力。
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Decreased phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) in type-1 diabetes.1型糖尿病中吞噬作用和抗体依赖性细胞毒性（ADCC）降低。
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Clinical disorders of leukocyte functions.白细胞功能的临床紊乱
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7
The function of the phagocytic leucocytes in leukaemia.白血病中吞噬性白细胞的功能。
Br J Haematol. 1972 Sep;23:Suppl:223-30. doi: 10.1111/j.1365-2141.1972.tb03522.x.
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Reduced phagocytosis promoting activity of saliva from patients with chronic lymphocytic leukemia.
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Age differences in phagocytosis by polymorphonuclear leukocytes measured by flow cytometry.通过流式细胞术测量的多形核白细胞吞噬作用中的年龄差异。
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Age-related changes in functions of peripheral blood phagocytes.外周血吞噬细胞功能的年龄相关变化。
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