Okamura K, Kuramoto M, Hamazaki Y, Suzuki M
Tohoku J Exp Med. 1978 Nov;126(3):235-8. doi: 10.1620/tjem.126.235.
Human chorionic gonadotropin (HCG) and steroid hormones were tested for their direct effects on murine lymphocyte humoral response to sheep RBCs using an in vitro culture system. A significant increase in plaque forming cells (PFC) was induced by the addition of HCG at a dose of either 50 i.u. or 500 i.u. However, no increase was observed by the addition of steroid hormones. HCG may contribute to the success of fetal allografts by increasing the number of blocking antibodies in the early stages of pregnancy.
利用体外培养系统，检测了人绒毛膜促性腺激素（HCG）和甾体激素对小鼠淋巴细胞对绵羊红细胞体液免疫反应的直接影响。添加50国际单位或500国际单位剂量的HCG可诱导空斑形成细胞（PFC）显著增加。然而，添加甾体激素未观察到增加。HCG可能通过在妊娠早期增加封闭抗体的数量，有助于胎儿同种异体移植的成功。
