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皮肤病患者血清妊娠相关α2-糖蛋白(α2-PAG,妊娠区蛋白,PZ)的浓度(作者译)

[Serum concentration of pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG, protein of pregnancy zone, PZ) in patients with dermatological diseases (author's transl)].

作者信息

Mattheus A, Hofmann R, Straube W

出版信息

Zentralbl Gynakol. 1981;103(16):946-51.

PMID:7347058
Abstract

Radial immunodiffusion, according to Mancini, was applied to 15 hospitalised patients, both during and after hospitalisation. They were of both sexes and all afflicted with dermatological diseases (psoriasis, eczema, mycosis). Determination of serum concentration of pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG, PZ) was the purpose of the tests. While in the acute phase of the disease the PZ serum levels of the three groups of patients were higher than those recorded from a control group, conventional therapy failed to have any impact upon PZ serum concentration. Continuous decline in PZ serum concentration was recordable from psoriasis patients in response to photochemotherapy (PUVA).

摘要

根据曼奇尼方法,对15名住院患者在住院期间及出院后均进行了放射免疫扩散检测。患者包括男性和女性,均患有皮肤病(牛皮癣、湿疹、真菌病)。检测目的是测定血清中妊娠相关α2 -糖蛋白(α2 -PAG,PZ)的浓度。在疾病急性期,三组患者的PZ血清水平均高于对照组,但常规治疗对PZ血清浓度没有任何影响。牛皮癣患者接受光化学疗法(PUVA)后,PZ血清浓度持续下降。

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