组胺受体拮抗剂对犬海登海因小胃黏膜胆汁损伤的影响。
Effect of histamine receptor antagonists on bile damage to the gastric mucosa of canine Heidenhain pouches.
作者信息
Rees W D, Rhodes J, Wheeler M H, Meek E M, Williams B, Newcombe R G
出版信息
Gut. 1977 Oct;18(10):821-6. doi: 10.1136/gut.18.10.821.
Abstract
The net ionic fluxes of H+ and Na+ were examined in Heidenhain pouches during damage with sodium taurocholate solution. The increase in ionic flux which occurred with taurocholate could be prevented in animals given H1 and H2 histamine antagonists in combination. The results suggest that histamine mediates changes in the transmucosal ionic flux produced by bile acid.
摘要
在用牛磺胆酸钠溶液造成损伤的过程中，对海登海因小胃中的H⁺和Na⁺净离子通量进行了检测。在联合给予H1和H2组胺拮抗剂的动物中，可防止牛磺胆酸钠引起的离子通量增加。结果表明，组胺介导了胆汁酸产生的跨粘膜离子通量变化。
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Cellular location of the electrical potential difference in frog gastric mucosa.青蛙胃黏膜中电位差的细胞定位。
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The anti-anaphylactic and histamine-releasing properties of the antihistamines. Their effect on the mast cells.抗组胺药的抗过敏和组胺释放特性。它们对肥大细胞的作用。
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Histamine release by antihistamines.抗组胺药引起的组胺释放。
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