Pingleton S K, Bone R C, Ruth W C
Crit Care Med. 1980 Jan;8(1):50-3. doi: 10.1097/00003246-198001000-00010.
Fiberoptic bronchoscopy in mechanically ventilated patients has been limited to endotracheal tubes of 8.0--8.5 mm diameter. When performed through smaller tubes, pressures exceeding ventilator limits may occur, alveolar ventilation may become impaired, or progressive hyperinflation from airway obstruction during expiration may result. In this study, the efficacy of a 70% helium-30% oxygen ventilating gas mixture was compared to 30% oxygen in air in a laboratory mechanical lung analog and during 15 bronchoscopies in 7 intubated patients. One patient with a 7.5 mm tube was studied. With the helium-oxygen mixture, ventilator pressures were not exceeded, alveolar ventilation was uncompromised, and hyperinflation did not occur. Bronchoscopy may be safely performed through endotracheal tubes smaller than 8.0 mm using a helium-oxygen mixture.
机械通气患者的纤维支气管镜检查一直局限于直径8.0 - 8.5毫米的气管内导管。当通过较细的导管进行检查时，可能会出现超过呼吸机限制的压力，肺泡通气可能会受损，或者在呼气期间因气道阻塞导致进行性肺过度充气。在本研究中，在实验室机械肺模拟装置以及对7例插管患者进行的15次支气管镜检查过程中，将70%氦气 - 30%氧气的通气混合气体与空气中30%氧气进行了比较。研究了1例使用7.5毫米导管的患者。使用氦氧混合气体时，未超过呼吸机压力，肺泡通气未受影响，且未发生肺过度充气。使用氦氧混合气体可安全地通过小于8.0毫米的气管内导管进行支气管镜检查。
