重症监护病房中的氦氧混合气体。
Helium oxygen mixtures in the intensive care unit.
作者信息
Chevrolet J C
机构信息
University Hospital, Geneva, Switzerland.
出版信息
Crit Care. 2001 Aug;5(4):179-81. doi: 10.1186/cc1019. Epub 2001 Jul 13.
Abstract
Heliox, a mixture of helium and oxygen, has a density that is less than that of air. Breathing heliox leads to a reduction in resistance to flow within the airways, and consequently to a decrease in the work of breathing (WOB), particularly in disorders that are characterized by increased airways resistance. Beneficial effects have been observed in patients with asthma, chronic obstructive pulmonary disease (COPD), bronchiolitis, bronchopulmonary dysplasia and upper airways obstruction. Until we have conclusive data that attest to the efficacy of heliox in such conditions, its use will remain controversial. Meanwhile, it appears wise not to incorporate heliox therapy into routine practice because of technical complications and high costs.
摘要
氦氧混合气是一种氦气和氧气的混合物，其密度小于空气。吸入氦氧混合气会使气道内的气流阻力降低，从而导致呼吸功（WOB）减少，尤其是在以气道阻力增加为特征的疾病中。在哮喘、慢性阻塞性肺疾病（COPD）、细支气管炎、支气管肺发育不良和上气道梗阻患者中已观察到有益效果。在我们有确凿数据证明氦氧混合气在这些情况下的疗效之前，其使用仍将存在争议。同时，由于技术并发症和高成本，不将氦氧混合气治疗纳入常规实践似乎是明智的。
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