Norman D A, Morawski S G, Fordtran J S
Gastroenterology. 1980 Jan;78(1):22-5.
The first experiment demonstrated that glucose stimulated calcium absorption. Possible mechanisms include: (a) glucose stimulation of active calcium absorption, (b) glucose stimulation of water absorption with enhanced calcium absorption by solvent drag, or (c) glucose stimulation of water absorption caused an increased luminal calcium concentration with resultant increased active and/or passive calcium absorption. In a second experiment, neither glucose, fructose of water absorption stimulated calcium absorption when luminal calcium concentration was maintained at a constant level. These results suggest: (a) glucose and fructose indirectly enhance calcium absorption via an effect on water movement, (b) water absorption enhances calcium absorption by virtue of concentrating unabsorbed calcium within the intestinal lumen, not by solvent drag, and (c) bulk water movement and passive calcium ion movement take place via separate channels.
第一个实验表明葡萄糖能刺激钙的吸收。可能的机制包括：(a) 葡萄糖刺激主动钙吸收；(b) 葡萄糖刺激水吸收，通过溶剂拖曳增强钙吸收；或 (c) 葡萄糖刺激水吸收导致肠腔钙浓度增加，从而使主动和/或被动钙吸收增加。在第二个实验中，当肠腔钙浓度保持在恒定水平时，葡萄糖、果糖或水吸收均未刺激钙吸收。这些结果表明：(a) 葡萄糖和果糖通过对水运动的影响间接增强钙吸收；(b) 水吸收通过将未吸收的钙集中在肠腔内来增强钙吸收，而非通过溶剂拖曳；(c) 大量水运动和被动钙离子运动通过不同通道进行。
