Blouin P, Cello R M
Invest Ophthalmol Vis Sci. 1980 Jan;19(1):21-30.
Ocular cryptococcosis was produced in cats by the intracarotid injection of Cryptococcus neoformans. Infected eyes developed a progressive, multifocal chorioretinitis which was comparable to that found in the naturally occurring feline disease. The severity of the ocular disease, the development of infection in the fellow eye, and the degree of systemic involvement were shown to be related to the number of organisms inoculated. Mice infected intracerebrally with the same organism developed optic nerve meningitis. The pathogenesis of the ocular lesions thus produced is discussed.
通过颈内注射新型隐球菌在猫身上引发眼部隐球菌病。受感染的眼睛出现进行性多灶性脉络膜视网膜炎，这与自然发生的猫科动物疾病中发现的情况相似。眼部疾病的严重程度、对侧眼感染的发展以及全身受累程度与接种的病原体数量有关。脑内感染相同病原体的小鼠出现视神经脑膜炎。本文讨论了由此产生的眼部病变的发病机制。
