Staib F, Mishra S K
Zentralbl Bakteriol Orig A. 1975 Jul;232(2-3):355-64.
During the course of infection in intraperitoneally infected white mice with a particular strain of Cryptococcus neoformans, it was possible to observe a time-limited and selective presence of the fungus in the brain. The presence of the fungus in the brain without causing clinical symptoms and the rare mortal exacerbation of the brain involvement offers possibilities for comparative studies of experimental and human cryptococcosis. On the basis of these strain-specific results new aspects of the virulence of C. neoformans and the epidemiology of cryptococcosis are discussed.
在用特定新型隐球菌菌株腹腔感染小白鼠的感染过程中，有可能观察到该真菌在脑部存在的时间限制和选择性。真菌在脑部存在却不引起临床症状，且脑部受累导致的罕见致命性加重，为实验性和人类隐球菌病的比较研究提供了可能性。基于这些菌株特异性结果，讨论了新型隐球菌毒力和隐球菌病流行病学的新方面。
