Clark J A, Finelli R E, Netsky M G
J Neurosurg. 1980 Feb;52(2):266-9. doi: 10.3171/jns.1980.52.2.0266.
Cranial and spinal trauma resulted in disseminated intravascular coagulation (DIC) in a 78-year-old man, causing widespread bleeding and incoagulable blood. Traumatized brain tissue was found in the lumina of dural venous sinuses. The mechanisms of DIC are reviewed. It is suggested that intravascular release of potent cerebral thromboplastin contributed to the severity of DIC in this patient, by causing activation of the extrinsic clotting system. Intrasinus brain tissue in cases of human trauma has not previously been reported.
一名78岁男性因颅脑和脊髓创伤导致弥散性血管内凝血（DIC），引起广泛出血和血液无法凝固。在硬脑膜静脉窦腔内发现了创伤性脑组织。本文对DIC的发病机制进行了综述。研究表明，强效脑凝血活酶的血管内释放激活了外源性凝血系统，从而加重了该患者DIC的严重程度。此前尚未有人类创伤病例中窦内脑组织的相关报道。
