Borah V, Shah P N, Ghosh S N, Sampat M B, Jussawalla D J
J Surg Oncol. 1980;13(1):1-7. doi: 10.1002/jso.2930130102.
Based on the Barr body frequency, a total of 285 unselected breast cancer tissues were categorised as negative and positive tumours; incidence of these two groups in our series was 2:1, respectively. When 2-years' disease-free interval and 10-years' survival were considered, it was seen that patients harbouring negative tumours had significantly early recurrence and shorter duration of survival as compared to those having positive tumours. As vascular spread is the prerequisite of early recurrence, the shorter survival in the patients having negative tumours could be explained on the basis of blood vessel invasion, in that 73% of the negative tumours had blood vessel invasion, in contrast to only 24% in the positive tumours.
根据巴氏小体频率，共285例未经选择的乳腺癌组织被分为阴性和阳性肿瘤；在我们的系列研究中，这两组的发生率分别为2:1。当考虑2年无病生存期和10年生存率时，发现与阳性肿瘤患者相比，阴性肿瘤患者的复发明显更早，生存期更短。由于血管播散是早期复发的前提，阴性肿瘤患者生存期较短可基于血管侵犯来解释，因为73%的阴性肿瘤有血管侵犯，而阳性肿瘤中只有24%有血管侵犯。
