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胸腺上皮细胞中表皮特异性异种抗原的显示。

Demonstration of epidermis-specific heteroantigens in thymic epithelial cells.

作者信息

Takigawa M, Imamura S, Ofuji S

出版信息

Int Arch Allergy Appl Immunol. 1977;55(1-6):58-60. doi: 10.1159/000231909.

DOI:10.1159/000231909
PMID:73519
Abstract

Heterologous anti-epidermal cell serum was obtained by immunizing rabbits with enzymatically dispersed, viable epidermal cells of guinea pigs, followed by absorption of the antiserum with red blood cells (sheep and guinea pig), lymphoid cells and liver powder (guinea pig). Immunofluorescence demonstrated that the antiserum reacted specifically with stratified squamous epithelial cells and thymus epithelial cells including Hassall's bodies of the guinea pig, monkey and man. It is suggested that the epithelial cells of the skin and thymus have common heteroantigens.

摘要

通过用酶分散的豚鼠活表皮细胞免疫兔子,然后用红细胞(绵羊和豚鼠)、淋巴细胞和肝粉(豚鼠)吸收抗血清,获得了异种抗表皮细胞血清。免疫荧光显示,该抗血清与豚鼠、猴子和人类的复层鳞状上皮细胞和胸腺上皮细胞(包括哈氏小体)发生特异性反应。提示皮肤和胸腺的上皮细胞具有共同的异种抗原。

相似文献

1
Demonstration of epidermis-specific heteroantigens in thymic epithelial cells.胸腺上皮细胞中表皮特异性异种抗原的显示。
Int Arch Allergy Appl Immunol. 1977;55(1-6):58-60. doi: 10.1159/000231909.
2
Experimental production of rabbit anti-guinea-pig epidermal cell sera. Comparison to pemphigus antibodies.兔抗豚鼠表皮细胞血清的实验制备。与天疱疮抗体的比较。
J Invest Dermatol. 1977 May;68(5):259-64. doi: 10.1111/1523-1747.ep12506651.
3
The human thymic microenvironment: thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation.人类胸腺微环境:胸腺上皮含有与表皮角质形成细胞成熟早期和晚期相关的特定角蛋白。
Differentiation. 1986;31(1):67-77. doi: 10.1111/j.1432-0436.1986.tb00385.x.
4
Expression of common cytoplasmic antigens by epithelial cells of thymus and epidermis.胸腺和表皮的上皮细胞对常见细胞质抗原的表达。
Arch Dermatol Res. 1982;274(1-2):113-21. doi: 10.1007/BF00510365.
5
Antigenic thymus-epidermis relationships. Reactivity of a panel of anti-thymic cell monoclonal antibodies on human keratinocytes and Langerhans cells.抗原性胸腺-表皮关系。一组抗胸腺细胞单克隆抗体对人角质形成细胞和朗格汉斯细胞的反应性。
Dermatologica. 1987;175(3):109-20.
6
Detection of squamous epithelial intercellular substance antigen(s) in Hassall's corpuscles of human and animal thymus.在人和动物胸腺的哈氏小体中检测鳞状上皮细胞间物质抗原。
Scand J Immunol. 1980;12(2):93-8. doi: 10.1111/j.1365-3083.1980.tb00045.x.
7
Binding specificity of rabbit anti-guinea pig epidermal cell sera: comparison of their receptors with those of concanavalin A and pemphigus sera.兔抗豚鼠表皮细胞血清的结合特异性:其受体与伴刀豆球蛋白A及天疱疮血清受体的比较
Acta Derm Venereol. 1979;59(2):113-9.
8
Reaction of sera of patients with pemphigus vulgaris with antigens of the cementing substance from the epithelium of Hassall's corpuscles of the human and animal thymus.寻常型天疱疮患者血清与人及动物胸腺哈氏小体细胞上皮黏附物质抗原的反应。
Bull Exp Biol Med. 1974 Dec;77(6):678-81. doi: 10.1007/BF00790000.
9
Granulocyte formation and infiltration in guinea-pig thymus following exposure to rabbit anti-thymus serum.豚鼠暴露于兔抗胸腺血清后胸腺中的粒细胞形成与浸润
J Anat. 1972 Feb;111(Pt 2):336.
10
Do epidermal cells produce thymic hormones in vivo? An immunohistochemical study using anti-thymic hormone antibodies.表皮细胞在体内会产生胸腺激素吗?一项使用抗胸腺激素抗体的免疫组织化学研究。
Thymus. 1988;12(3):187-201.

引用本文的文献

1
Functional anatomy of the thymic microenvironment.胸腺微环境的功能解剖学
J Anat. 1991 Aug;177:1-29.