吸烟者、不吸烟者和“对烟雾敏感者”对烟叶和烟雾抗原的IgE抗体反应。

IgE antibody response of smokers, nonsmokers, and "smoke-sensitive" persons to tobacco leaf and smoke antigens.

作者信息

Lehrer S B, Wilson M R, Karr R M, Salvaggio J E

出版信息

Am Rev Respir Dis. 1980 Jan;121(1):168-70. doi: 10.1164/arrd.1980.121.1.168.

DOI:10.1164/arrd.1980.121.1.168

Abstract

Serum samples from cigarette smokers, nonsmokers, and persons reporting "smoke sensitivity" were tested for IgE antibodies to tobacco leaf and smoke extracts by the radioallergosorbent test. Results indicated that none of the serum samples tested contained detectable IgE antibodies to smoke extracts. Occasionally, serum specimens from smokers or nonsmokers demonstrated reactivity to leaf antigen. The most significant reaction to leaf antigens was detected in serum from one of the 7 smoke-sensitive subjects tested. These results demonstrate that smoking, nonsmoking, and clinical "smoke sensitivity" are not correlated with the presence of IgE antibodies to tobacco leaf or smoke antigen.

摘要

通过放射变应原吸附试验，对吸烟者、不吸烟者以及自述“对烟雾敏感”者的血清样本进行了针对烟叶和烟雾提取物的IgE抗体检测。结果表明，所检测的血清样本中均未含有可检测到的针对烟雾提取物的IgE抗体。偶尔，吸烟者或不吸烟者的血清标本对叶片抗原有反应性。在7名接受检测的对烟雾敏感的受试者中，有1人的血清对叶片抗原有最显著的反应。这些结果表明，吸烟、不吸烟以及临床上的“对烟雾敏感”与针对烟叶或烟雾抗原的IgE抗体的存在无关。