Age-related symtomatology of ECHO 11 virus infection in children.

One hundred two children with ECHO 11 virus infection were analyzed as to symptomatology, which was related to the age of the patients. Neonates manifested an undifferentiated febrile illness in most cases. The symptomatology of older infants and toddlers was different from that of newborns with respect to the presence of discernible pharyngitis in two thirds of the cases. An exaggerated febrile response complicated by convulsions or gastrointestinal symptoms was another characteristic feature of this age group. A characteristic manifestation of children more than 3 years old was pharyngitis which included minute vesicular lesions or exudative ulcers around the fauces.