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[不同甲状腺功能状态下3,3',5'-三碘甲腺原氨酸(反式三碘甲腺原氨酸)的血浆水平]

[Plasma levels of 3,3', 5'-T3 (reverse-T3) under various functional thyroid conditions].

作者信息

Hüfner M, Grussendorf M, Knöpfle M

出版信息

Acta Biol Med Ger. 1978;37(3):447-52.

PMID:735616
Abstract

Reverse T3 (r-T3) was measured in unextracted human plasma under different clinical conditions. The mean normal concentration was 0.20 ng/ml. In thyreotoxic patients r-T3 was elevated in the majority of the cases, however, it was normal in three cases of T3-toxicoses. Thyrectomized patients during different hormon substitution showed r-T3 levels corresponding to the T4 concentrations measured. Patients with severe chronic illnesses and low T3 showed normal to considerably elevated r-T3 levels. According to these results r-T3 is not of additional value in the diagnosis of thyroid disorders.

摘要

在不同临床情况下,对未提取的人血浆中的反三碘甲状腺原氨酸(r-T3)进行了测量。正常平均浓度为0.20纳克/毫升。在甲状腺毒症患者中,大多数病例的r-T3升高,然而,在三例三碘甲状腺原氨酸毒性病例中r-T3正常。不同激素替代治疗期间的甲状腺切除患者显示r-T3水平与所测甲状腺素(T4)浓度相对应。患有严重慢性疾病且三碘甲状腺原氨酸(T3)水平低的患者,其r-T3水平正常至显著升高。根据这些结果,r-T3在甲状腺疾病的诊断中并无额外价值。

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