Branch C D, Ebenstein R S, Borgia J F, Horvath S M, Preston F W
Surg Gynecol Obstet. 1980 Mar;150(3):353-6.
Dogs having a jejunoileal bypass, with the distal end of the bypassed segment being exteriorized as an ileal stoma, were compared with a control group having a Payne type jejunoileal bypass. In both groups, approximately 83 percent of the small intestine was bypassed. All except one dog survived the full six months of the study. During the first four months after the jejunoileal bypass, the dogs having an ileal stoma had more stable food consumption, less weight loss and higher levels of serum albumin than did those of the control group. During this period the bypassed segment in dogs of the control group usually contained bacteroides, whereas, after ileostomy, the segments were usually free of these organisms. At six months after jejunoileal bypass, there was no significant difference in the two groups with regard to nutrition, weight and the presence of bacteroides in the excluded segment. The hepatic structure and function was unaffected by both bypass procedures. Following a jejunoileal bypass in the dog, the complications associated with the excluded segment can be lessened by exteriorizing the distal end of the segment as a cutaneous ileal stoma.
将接受空肠回肠旁路手术且被旁路的肠段远端外置形成回肠造口的狗,与接受佩恩(Payne)式空肠回肠旁路手术的对照组狗进行比较。两组中,约83%的小肠被旁路。除一只狗外,所有狗均存活了整个六个月的研究期。在空肠回肠旁路手术后的前四个月,有回肠造口的狗食物摄入量更稳定,体重减轻更少,血清白蛋白水平高于对照组。在此期间,对照组狗的旁路肠段通常含有拟杆菌,而在回肠造口术后,这些肠段通常没有这些微生物。空肠回肠旁路手术后六个月,两组在营养、体重及被排除肠段中拟杆菌的存在方面无显著差异。两种旁路手术均未影响肝脏结构和功能。在狗进行空肠回肠旁路手术后,将肠段远端作为皮肤回肠造口外置,可以减轻与被排除肠段相关的并发症。