Efficacy of albendazole against Fasciola hepatica in cattle.

Albendazole in drench formulation was administered to calves 16 weeks after infection with 400 metacercariae of Fasciola hepatica. In separate experiments, albendazole at dose levels of 10 or 15 mg/kg reduced the fluke burden by 92.84 per cent and 95.0 per cent, respectively. In another experiment, a dose level of 7.5 mg/kg given once, twice with a two-week interval, or twice with a three-week interval reduced the mean fluke burden by 43.75 per cent, 72.29 per cent and 90 per cent, respectively.