Narbaitz R, Stumpf W E, Sar M
Anat Embryol (Berl). 1980;158(2):161-6. doi: 10.1007/BF00315903.
Swiss albino mice were injected on day 16 of pregnancy with 3H diethylstilbestrol. Fetuses were sacrificed 3 h afterwards, frozen, and processed for thaw-mount autoradiography. The serial sections from 4 fetuses were studied. Intense nuclear concentration of radioactivity was found in the mesenchymal cells directly surrounding the epithelial primordia of the mammary glands, but not in the epithelium itself. Localization was similar in male and female fetuses. These findings are discussed in relation to their developmental, teratological, and onocological implications.
在怀孕第16天给瑞士白化小鼠注射3H己烯雌酚。3小时后处死胎儿，冷冻，并进行解冻装片放射自显影处理。研究了4个胎儿的连续切片。在乳腺上皮原基周围的间充质细胞中发现了强烈的放射性核浓聚，但上皮本身未发现。雄性和雌性胎儿的定位相似。结合其发育、致畸和肿瘤学意义对这些发现进行了讨论。
