Danon M, Weintraub B D, Kim S H, Scully R E, Crawford J D
J Pediatr. 1978 Jan;92(1):51-4. doi: 10.1016/s0022-3476(78)80069-9.
A 7-year-old boy with sexual precocity of recent onset was found to have elevated levels of chorionic gonadotropin, alpha fetoprotein, and testosterone. Removal of a retropleural, posterior mediastinal mass with an intraspinous epidural extension was followed by prompt declines in the plasma concentrations of the tumor markers and cessation of adolescent development. The neoplasm proved to be a polyembryoma, unusual in the multiplicity of its embryoid bodies and extra gonadal location. Following local irradiation and two years of systemic chemotherapy, the patient, now 13 years of age, has done well except for evidence of testicular tubular insufficiency.
一名近期出现性早熟的7岁男孩，其绒毛膜促性腺激素、甲胎蛋白和睾酮水平升高。切除一个伴有椎管内硬膜外扩展的胸膜后、后纵隔肿块后，肿瘤标志物的血浆浓度迅速下降，青春期发育停止。该肿瘤被证实为多胚瘤，其胚体的多样性和性腺外位置都很不寻常。经过局部放疗和两年的全身化疗后，现年13岁的患者情况良好，只是有睾丸曲细精管功能不全的迹象。
