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产后营养不良对背侧海马癫痫样点燃的影响。

The effect of postnatal undernourishment on epileptiform kindling of dorsal hippocampus.

作者信息

Taber K H, Fuller G N, Stanley J C, DeFrance J F, Wiggins R C

出版信息

Experientia. 1980 Jan 15;36(1):69-70. doi: 10.1007/BF02003979.

DOI:10.1007/BF02003979
PMID:7358137
Abstract

Rats were undernourished postnatally from birth through 20 days of age. They were subsequently tested for susceptibility to motor seizures kindled in hippocampus in adulthood. Compared to littermate control animals the postnatally undernourished rats were more susceptible to the kindling treatment. We conclude that early postnatal undernourishment has a permanent effect on susceptibility of the hippocampus to electrically-induced seizures.

摘要

大鼠从出生到20日龄处于出生后营养不良状态。随后对它们进行测试,以检测成年后海马体中运动性癫痫发作的易感性。与同窝对照动物相比,出生后营养不良的大鼠对点燃处理更敏感。我们得出结论,出生后早期营养不良对海马体对电诱导癫痫发作的易感性有永久性影响。

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1
The effect of postnatal undernourishment on epileptiform kindling of dorsal hippocampus.产后营养不良对背侧海马癫痫样点燃的影响。
Experientia. 1980 Jan 15;36(1):69-70. doi: 10.1007/BF02003979.
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Exogenous antenatal glucocorticoid treatment reduces susceptibility for hippocampal kindled and maximal electroconvulsive seizures in infant rats.外源性产前糖皮质激素治疗可降低幼鼠海马点燃和最大电惊厥发作的易感性。
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Resistance of immature hippocampus to morphologic and physiologic alterations following status epilepticus or kindling.未成熟海马体对癫痫持续状态或点燃后形态学和生理学改变的抵抗性。
Hippocampus. 2001;11(6):615-25. doi: 10.1002/hipo.1076.
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Increased susceptibility to pentylenetetrazol-induced seizures in adult rats following electrical kindling during brain development.在脑发育过程中经电刺激点燃后成年大鼠对戊四氮诱导惊厥的易感性增加。
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A single neonatal pentylenetetrazol or hyperthermia convulsion increases kindling susceptibility in the adult rat.单次新生大鼠戊四氮或高热惊厥会增加成年大鼠的点燃易感性。
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Secondary generalization of hippocampal kindled seizures in rats: examining the role of the piriform cortex.大鼠海马点燃癫痫的继发性泛化:探讨梨状皮质的作用。
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Lasting effects of acute dehydration and post-weaning undernourishment on cortical spreading depression in adult rats.
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本文引用的文献

1
The role of nutrition in the development of evoked cortical responses in rat.营养在大鼠诱发皮质反应发育中的作用。
Brain Res. 1967 Oct;6(2):241-51. doi: 10.1016/0006-8993(67)90194-1.
2
A permanent change in brain function resulting from daily electrical stimulation.每日电刺激导致的大脑功能永久性改变。
Exp Neurol. 1969 Nov;25(3):295-330. doi: 10.1016/0014-4886(69)90128-9.
3
Nutritional influences upon somatosensory evoked responses during development in the rat.营养对大鼠发育过程中体感诱发电位的影响。
Physiol Behav. 1973 Jun;10(6):1019-22. doi: 10.1016/0031-9384(73)90182-0.
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Synthesis of myelin proteins during starvation.饥饿期间髓磷脂蛋白的合成。
Brain Res. 1974 Nov 15;80(2):345-9. doi: 10.1016/0006-8993(74)90698-2.
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Myelin synthesis during postnatal nutritional deprivation and subsequent rehabilitation.
Brain Res. 1976 May 7;107(2):257-73. doi: 10.1016/0006-8993(76)90225-0.
6
EEG development in normal and undernourished rats.正常和营养不良大鼠的脑电图发育
Brain Res. 1976 Mar 26;105(2):287-308. doi: 10.1016/0006-8993(76)90426-1.
7
The effect of chronic protein malnutrition on trans-callosal evoked responses in the rat.慢性蛋白质营养不良对大鼠胼胝体诱发反应的影响。
Dev Psychobiol. 1975 Nov;8(6):503-9. doi: 10.1002/dev.420080606.
8
Primary and "transfer" seizure development in the kindled rat.点燃大鼠的原发性和“转移性”癫痫发作发展
Can J Neurol Sci. 1975 Nov;2(4):417-28. doi: 10.1017/s0317167100020564.
9
Effect of chronic protein malnutrition on non-specific thalamo-cortical evoked potentials in the rat.慢性蛋白质营养不良对大鼠非特异性丘脑-皮质诱发电位的影响。
Physiol Behav. 1975 May;14(5):655-8. doi: 10.1016/0031-9384(75)90195-x.
10
Cortical and caudate spreading depression as an indicator of neural changes induced by early malnutrition in rats [proceedings].皮质和尾状核扩散性抑制作为大鼠早期营养不良所致神经变化的指标[会议论文集]
Act Nerv Super (Praha). 1977 May;19(2):130-1.