Taber K H, Fuller G N, Stanley J C, DeFrance J F, Wiggins R C
Experientia. 1980 Jan 15;36(1):69-70. doi: 10.1007/BF02003979.
Rats were undernourished postnatally from birth through 20 days of age. They were subsequently tested for susceptibility to motor seizures kindled in hippocampus in adulthood. Compared to littermate control animals the postnatally undernourished rats were more susceptible to the kindling treatment. We conclude that early postnatal undernourishment has a permanent effect on susceptibility of the hippocampus to electrically-induced seizures.
大鼠从出生到20日龄处于出生后营养不良状态。随后对它们进行测试,以检测成年后海马体中运动性癫痫发作的易感性。与同窝对照动物相比,出生后营养不良的大鼠对点燃处理更敏感。我们得出结论,出生后早期营养不良对海马体对电诱导癫痫发作的易感性有永久性影响。