Nemoto K, Ohnishi Y, Tsukada T
Acta Pathol Jpn. 1978 Sep;28(5):797-805. doi: 10.1111/j.1440-1827.1978.tb00918.x.
An autopsy case of a 33 years old doctor with chronic lymphocytic leukemia (CLL) was reported. Two remissions were noted with chemotherapy and irradiation. The special characteristic of this case was the tumor formation in the sellar fossa similating a pituitary tumor which was considered as a type of meningeal leukemia, showing visual disturbance. Leukemic cell infiltration was hardly observed in any other organs. From the analysis of five cases of CLL, the author proposes that CLL may be classified into two types: the one is the severe type showing a short clinical course and the other is a mild one, showing a long clinical course. Details such as histopathological findings, cause of death and clinical findings were discussed.
报告了一例33岁慢性淋巴细胞白血病（CLL）医生的尸检病例。经化疗和放疗后出现两次缓解。该病例的特殊之处在于蝶鞍区形成肿瘤，类似垂体瘤，被认为是脑膜白血病的一种类型，表现为视力障碍。在其他任何器官中几乎未观察到白血病细胞浸润。通过对5例CLL病例的分析，作者提出CLL可分为两种类型：一种是临床病程短的严重型，另一种是临床病程长的轻型。讨论了组织病理学表现、死因及临床发现等细节。
