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人体内阿片肽对血管加压素释放的内源性控制的证据。

Evidence for endogenous opioid control of vasopressin release in man.

作者信息

Lightman S L, Forsling M L

出版信息

J Clin Endocrinol Metab. 1980 Mar;50(3):569-71. doi: 10.1210/jcem-50-3-569.

DOI:10.1210/jcem-50-3-569
PMID:7358835
Abstract

The role of endogenous opioids in the control of vasopressin secretion was studied using the pure opiate antagonist naloxone. Naloxone both reduced resting levels of vasopressin and inhibited the rise in vasopressin induced by an orthostatic stimulus. These results suggest that endogenous opioids are important as a tonic stimulus to vasopressin release in man.

摘要

利用纯阿片拮抗剂纳洛酮研究了内源性阿片类物质在抗利尿激素分泌控制中的作用。纳洛酮既能降低抗利尿激素的静息水平，又能抑制由直立位刺激引起的抗利尿激素升高。这些结果表明，内源性阿片类物质作为对人体抗利尿激素释放的一种紧张性刺激是很重要的。

相似文献

1
Evidence for endogenous opioid control of vasopressin release in man.人体内阿片肽对血管加压素释放的内源性控制的证据。
J Clin Endocrinol Metab. 1980 Mar;50(3):569-71. doi: 10.1210/jcem-50-3-569.
2
Opioid-noradrenergic interactions in the neurohypophysis. II. Does noradrenaline mediate the actions of endogenous opioids on oxytocin and vasopressin release?神经垂体中的阿片类物质 - 去甲肾上腺素相互作用。II. 去甲肾上腺素是否介导内源性阿片类物质对催产素和血管加压素释放的作用？
Neuroendocrinology. 1988 Jul;48(1):25-31. doi: 10.1159/000124985.
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Endogenous opioids inhibit oxytocin release during nicotine-stimulated secretion of vasopressin in man.内源性阿片肽在尼古丁刺激人血管加压素分泌过程中抑制催产素释放。
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Drinking and subsequent suppression of vasopressin is unaltered by naloxone in dogs.在狗身上，饮酒及随后抗利尿激素的抑制作用不会因纳洛酮而改变。
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Hypoglycemia-induced suppression of luteinizing hormone (LH) secretion in intact female rhesus macaques: role of vasopressin and endogenous opioids.
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引用本文的文献

1
Naloxone decreases the inhibitory effect of ethanol on the release of arginine-vasopressin induced by physical exercise in man.纳洛酮可降低乙醇对人体运动诱导的精氨酸加压素释放的抑制作用。
J Neural Transm (Vienna). 2009 Sep;116(9):1065-9. doi: 10.1007/s00702-009-0270-5. Epub 2009 Aug 1.
2
Effect of naloxone on somatostatin inhibition of arginine vasopressin response to physical exercise in normal men.纳洛酮对正常男性中生长抑素抑制精氨酸加压素对体育锻炼反应的影响。
J Neural Transm (Vienna). 2008 Jun;115(6):803-7. doi: 10.1007/s00702-008-0026-7. Epub 2008 Feb 8.
3
The effect of naloxone on vasopressin release from rat neurohypophysis incubated in vitro.
纳洛酮对体外培养的大鼠神经垂体释放血管加压素的影响。
J Physiol. 1983 Aug;341:507-15. doi: 10.1113/jphysiol.1983.sp014820.
4
Evidence for a role of opioid peptides in the release of arginine vasopressin in the conscious rat.阿片肽在清醒大鼠中释放精氨酸加压素作用的证据。
J Clin Invest. 1982 Mar;69(3):666-72. doi: 10.1172/jci110494.
5
The effects of desmopressin on hemostatic parameters in the normal dog.去氨加压素对正常犬止血参数的影响。
Can J Vet Res. 1986 Apr;50(2):265-71.
6
Effect of naloxone on counter insulin hormone secretion in insulin-induced hypoglycemia.纳洛酮对胰岛素诱导的低血糖中对抗胰岛素激素分泌的影响。
Korean J Intern Med. 1987 Jul;2(2):190-5. doi: 10.3904/kjim.1987.2.2.190.
7
Metergoline, naloxone, and sodium valproate did not modify arginine vasopressin response to insulin-induced hypoglycemia in man.麦角苄酯、纳洛酮和丙戊酸钠不会改变人体中精氨酸加压素对胰岛素诱导的低血糖的反应。
J Endocrinol Invest. 1988 May;11(5):365-9. doi: 10.1007/BF03349056.