人体内阿片肽对血管加压素释放的内源性控制的证据。
Evidence for endogenous opioid control of vasopressin release in man.
作者信息
Lightman S L, Forsling M L
出版信息
J Clin Endocrinol Metab. 1980 Mar;50(3):569-71. doi: 10.1210/jcem-50-3-569.
PMID:7358835
Abstract
The role of endogenous opioids in the control of vasopressin secretion was studied using the pure opiate antagonist naloxone. Naloxone both reduced resting levels of vasopressin and inhibited the rise in vasopressin induced by an orthostatic stimulus. These results suggest that endogenous opioids are important as a tonic stimulus to vasopressin release in man.
摘要
利用纯阿片拮抗剂纳洛酮研究了内源性阿片类物质在抗利尿激素分泌控制中的作用。纳洛酮既能降低抗利尿激素的静息水平，又能抑制由直立位刺激引起的抗利尿激素升高。这些结果表明，内源性阿片类物质作为对人体抗利尿激素释放的一种紧张性刺激是很重要的。
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