Stubbs D F
Gut. 1977 Mar;18(3):202-7. doi: 10.1136/gut.18.3.202.
Some empirical and theoretical models of the emptying behaviour of the stomach are presented. The laws of Laplace, Hooke, and Poisseuille are used to derive a new model of gastric emptying. Published data on humans are used to test the model and evaluate empirical constants. It is shown that for meals with an initial volume of larger than or equal to 300 ml, the reciprocal of the cube root of the volume of meal remaining is proportional to the time the meal is in the stomach. For meals of initial volume of less than 300 ml the equation has to be corrected for the fact that the 'resting volume' of gastric contents is about 28 ml. The more exact formula is given in the text. As this model invokes no neural or hormonal factors, it is suggested that the gastric emptying response to the volume of a meal does not depend on these factors. The gastric emptying response to the composition of the meal does depend on such factors and a recent model of this process is used to evaluate an empirical constant.
本文介绍了一些关于胃排空行为的经验模型和理论模型。利用拉普拉斯定律、胡克定律和泊肃叶定律推导出一个新的胃排空模型。采用已发表的人体数据对该模型进行检验并评估经验常数。结果表明，对于初始体积大于或等于300毫升的餐食，剩余餐食体积立方根的倒数与餐食在胃内停留的时间成正比。对于初始体积小于300毫升的餐食，由于胃内容物的“静息体积”约为28毫升，该方程必须进行修正。文中给出了更精确的公式。由于该模型未涉及神经或激素因素，因此表明胃对餐食体积的排空反应不依赖于这些因素。胃对餐食成分的排空反应确实依赖于这些因素，并且利用最近的一个该过程模型来评估一个经验常数。
