Ting-Beall H P
J Microsc. 1980 Feb;118(2):221-7. doi: 10.1111/j.1365-2818.1980.tb00264.x.
Uranyl ions (UO2(2+)), once bound to the phosphate moieties of phospholipid head groups, stabilize bimolecular lipid membranes (BLMs) as well as decrease the nonactin-induced membrane conductance. UO2(2+) bind to a phosphatidyl choline-cholesterol (2:1, molar ratio) BLM surface with a dissociation constant of 2.3 microM and a maximum change in surface potential of 88 mV, which corresponds approximately to one uranyl ion per 31 nm2 surface area. Furthermore, uranyl ions can penetrate the lipid bilayers as neutral complexes such as uranyl acetate.
铀酰离子（UO2(2+)）一旦与磷脂头部基团的磷酸部分结合，就能稳定双分子脂质膜（BLM），并降低缬氨霉素诱导的膜电导。UO2(2+)以2.3微摩尔的解离常数和88毫伏的最大表面电位变化与磷脂酰胆碱 - 胆固醇（摩尔比2:1）BLM表面结合，这大约相当于每31平方纳米表面积有一个铀酰离子。此外，铀酰离子可以作为中性络合物（如醋酸铀酰）穿透脂质双层。
