Glass E C, DeNardo G L, Hines H H
Radiology. 1980 Apr;135(1):187-90. doi: 10.1148/radiology.135.1.7360959.
99mTc methylene diphosphonate (99mTc MDP) was evaluated as a clinical renal imaging agent in 20 patients referred for bone scintigraphy. Sequential scintigraphy, which was started immediately after injection, yielded blood flow studies of high quality, and subsequent images accurately delineated renal anatomy and excretion in nonazotemic patients. In comparison with delayed images, early images were vastly superior in quality and demonstrated improved target-to-nontarget activity ratios(p less than 0.001) and improved lesion detectability (p less than 0.01). Renal imaging performed incidental to bone scintigraphy with MDP can be greatly enhanced by initiating sequential scintigraphy immediately after injection.
对20例因骨闪烁扫描而转诊的患者，评估了99m锝亚甲基二膦酸盐（99mTc MDP）作为临床肾脏显像剂的效果。注射后立即开始的连续闪烁扫描获得了高质量的血流研究结果，随后的图像准确描绘了非氮质血症患者的肾脏解剖结构和排泄情况。与延迟图像相比，早期图像在质量上有很大优势，显示出更高的靶与非靶活性比（p<0.001）和更好的病变可检测性（p<0.01）。通过注射后立即开始连续闪烁扫描，可大大提高与MDP骨闪烁扫描同时进行的肾脏显像效果。
