Rees P J, Chilvers C, Clark T J
Thorax. 1980 Jan;35(1):47-51. doi: 10.1136/thx.35.1.47.
We have compared estimation of alveolar carbon monoxide measured either as end-expired or mixed-expired carbon monoxide tension with two spectrophotometric estimations of venous blood carboxyhaemoglobin (COHb). Estimation of mixed-expired carbon monoxide proved more convenient for patients than the end-expired method, and this estimation of carbon monoxide exposure discriminated between non-smokers and smokers as well as measurements of COHb. The technique is bloodless, economical, and simple to perform. It should prove a valuable method for validating reported smoking habits of people attending smoking advisory centres and for epidemiological surveys of smoking.
我们已将通过测定终末呼出或混合呼出一氧化碳分压来估算肺泡一氧化碳，与两种分光光度法测定静脉血中碳氧血红蛋白（COHb）进行了比较。结果表明，对于患者而言，测定混合呼出一氧化碳比测定终末呼出一氧化碳更方便，而且这种对一氧化碳暴露的估算在区分非吸烟者和吸烟者方面与测定碳氧血红蛋白的效果一样好。该技术无需采血，经济且操作简单。它应是一种有价值的方法，可用于验证前往吸烟咨询中心人员所报告的吸烟习惯，以及用于吸烟的流行病学调查。
