Patnaik A K, Hurvitz A I, Johnson G F
Vet Pathol. 1980 Mar;17(2):149-63. doi: 10.1177/030098588001700204.
Thirty-one of 35 canine intestinal neoplasms were adenocarcinomas and four were carcinoids. Acinar, solid, papillary and mucinous adenocarcinomas were seen. Acinar and papillary adenocarcinomas were more common the duodenum, colon and rectum. Papillary adenocarcinomas involved longer segments of the intestine. Mucinous adenocarcinomas were in all segments of the intestines but were more frequent in the jejunum. The only signet ring cell carcinoma occurred in the duodenum. Carcinoids occurred equally in the duodenum and colon. Half the rectal tumors showed transition from benign polypoid lesions to adenocarcinomas. Hyperplasia, branching of crypts, increase in goblet cells, and glandular fusion (some cells with anaplasia) were severe in the mucosa adjoining all neoplastic tissue. Local invasion was seen in 32 dogs. Lymph node, lungs, liver and intestinal wall were the most common sites of metastases, Half of the metastases in the liver were from carcinoids and were diffuse.
35例犬肠道肿瘤中，31例为腺癌，4例为类癌。可见腺泡状、实体状、乳头状和黏液性腺癌。腺泡状和乳头状腺癌在十二指肠、结肠和直肠更为常见。乳头状腺癌累及的肠段更长。黏液性腺癌可见于肠道各段，但在空肠更为常见。唯一的印戒细胞癌发生在十二指肠。类癌在十二指肠和结肠的发生率相同。一半的直肠肿瘤显示从良性息肉样病变转变为腺癌。在所有肿瘤组织相邻的黏膜中，增生、隐窝分支、杯状细胞增多和腺体融合（一些细胞间变）都很严重。32只犬出现局部浸润。淋巴结、肺、肝和肠壁是最常见的转移部位，肝转移中一半来自类癌，且为弥漫性转移。
