来自不同器官的细胞对氟化物的敏感性。
Fluoride sensitivity of cells from different organs.
作者信息
Hongslo C F, Hongslo J K, Holland R I
出版信息
Acta Pharmacol Toxicol (Copenh). 1980 Jan;46(1):73-7. doi: 10.1111/j.1600-0773.1980.tb02423.x.
Abstract
The fluoride sensitivity of cells released from rat livers and kidneys by collagenase perfusion was investigated by measuring effect on protein synthesis rate in vitro. Both cell types were sensitive to fluoride with clear concentration/effect relationships. Significant difference in sensitivity for fluoride between the cell types was found, with the kidney cells being the most sensitive type.
摘要
通过测量对体外蛋白质合成速率的影响，研究了用胶原酶灌注从大鼠肝脏和肾脏释放的细胞对氟化物的敏感性。两种细胞类型对氟化物均敏感，具有明确的浓度/效应关系。发现细胞类型之间对氟化物的敏感性存在显著差异，其中肾细胞是最敏感的类型。
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