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甲砜霉素和氯霉素:特别针对杀菌活性的体外比较

Thiamphenicol and chloramphenicol: an in vitro comparison with particular reference to bactericidal activity.

作者信息

O'Grady F, Pearson N J, Dennis C

出版信息

Chemotherapy. 1980;26(2):116-20. doi: 10.1159/000237892.

Abstract

Chloramphenicol is bacteristatic for most species but bactericidal for Haemophilus influenzae and Neisseria meningitidis. Despite its generally lower activity, thiamphenicol exhibited equal or greater activity against these two species than did chloramphenicol. It is suggested that a particular place might be defined for thiamphenicol in the treatment of infection due to these two organisms.

摘要

氯霉素对大多数菌种呈抑菌作用,但对流感嗜血杆菌和脑膜炎奈瑟菌具有杀菌作用。尽管甲砜霉素的活性总体较低,但其对这两种菌种的活性与氯霉素相当或更高。有人提出,在治疗由这两种微生物引起的感染时,甲砜霉素可能具有特殊地位。

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