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欧洲的非洲型伯基特淋巴瘤(作者译)

[Burkitt lymphoma of African type in Europe (author's transl)].

作者信息

Kachel G, Bornkamm G W, Hermanek P, Kaduk B, Schricker K T

出版信息

Dtsch Med Wochenschr. 1980 Mar 21;105(12):413-7. doi: 10.1055/s-2008-1070678.

Abstract

A 34-year-old German woman who had never been to Africa developed a Burkitt lymphoma of African type during the fifth month of pregnancy. The diagnosis was confirmed during life by cytological and virological tests. There was a markedly increased antibody titre against the Epstein-Barr virus in serum as well as virus antigen in the tumour tissue. There was extensive involvement of almost all abdominal organs and of the breast. After spontaneous abortion of a female foetus in the sixth month of pregnancy cytostatic treatment was started, but without achieving remission. The patient died five weeks after admission to hospital; the autopsy confirmed the clinical findings.

摘要

一名从未去过非洲的34岁德国女性在怀孕第五个月时患上了非洲型伯基特淋巴瘤。通过细胞学和病毒学检测在生前确诊。血清中针对爱泼斯坦-巴尔病毒的抗体滴度显著升高,肿瘤组织中也存在病毒抗原。几乎所有腹部器官和乳房都有广泛受累。在怀孕第六个月自然流产一名女胎后开始进行细胞抑制治疗,但未实现缓解。患者入院五周后死亡;尸检证实了临床发现。

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