Lundborg G, Rank F
Hand. 1980 Feb;12(1):3-11. doi: 10.1016/s0072-968x(80)80023-4.
An experimental model is presented to study superficial healing of animal and human flexor tendon in a synovial environment. The results indicate that in a synovial environment a cut and resutured flexor tendon may heal in its superficial parts without adhesion formation. When cell seeding via the synovial fluid is prevented by a dialysing membrane the picture, as revealed by light microscopy, is little changed. When the model is modified so that the central cells of the tendon are exposed to the synovial fluid, these cells become activated. The results indicate that superficial as well as deep cells of the tendon possess a potential for repair if they are adequately nourished, and that cell seeding plays no major role in the process of proliferation and repair. The picture of intrinsic repair potential in a synovial environment seems to be valid also for human flexor tendons.
本文提出了一种实验模型，用于研究在滑膜环境中动物和人类屈肌腱的表面愈合情况。结果表明，在滑膜环境中，切断并重新缝合的屈肌腱可能在其表面部分愈合而不形成粘连。当通过透析膜阻止滑膜液进行细胞接种时，光镜观察显示情况变化不大。当对模型进行改进，使肌腱的中央细胞暴露于滑膜液中时，这些细胞会被激活。结果表明，如果肌腱的表面和深部细胞得到充分滋养，它们具有修复潜力，并且细胞接种在增殖和修复过程中不起主要作用。滑膜环境中内在修复潜力的情况似乎对人类屈肌腱也适用。
