Lundborg G, Rank F
J Hand Surg Am. 1978 Jan;3(1):21-31. doi: 10.1016/s0363-5023(78)80114-2.
The healing process of totally cut and subsequently resutured rabbit flexor tendons kept isolated in the knee joint cavity and free in the synovial fluid was studied by histological and ultrastructural techniques. This experimental model represents a "tissue culture in situ," where the tendon is nourished by diffusion from the synovial fluid only and where no adhesions are formed. Under these conditions there is a proliferation of tendon cells and deposition of collagen resulting in bridging of the suture line. On the basis of these findings, it is assumed that the tendon cells possess an intrinsic potential of repair, provided they obtain a sufficient nutritional supply. In the present experimental model, this nutrition was provided by way of diffusional pathways from the synovial fluid.
通过组织学和超微结构技术研究了完全切断并随后缝合的兔屈肌腱在膝关节腔内隔离且在滑液中自由的愈合过程。该实验模型代表一种“原位组织培养”，在此模型中，肌腱仅通过滑液扩散获得营养，且不会形成粘连。在这些条件下，肌腱细胞增殖并沉积胶原蛋白，导致缝线处形成桥接。基于这些发现，假设只要肌腱细胞获得足够的营养供应，它们就具有内在的修复潜力。在本实验模型中，这种营养是通过滑液的扩散途径提供的。
