Wright D J, Woodrow D F
J Pathol. 1980 Feb;130(2):83-90. doi: 10.1002/path.1711300204.
The terminal changes following Borrelia duttoni infection in mice consisted of disseminated intravascular coagulation with associated depression in temperature, and in white cell and platelet counts with the development of a positive limulus lysate test. Apart from thrombosis and haemorrhage, similar changes were found in mice given cyclophosphamide prior to infection. The results suggest that neither intravascular coagulation nor immune complex formation are major factors in causing death in borreliosis.
杜通疏螺旋体感染小鼠后的终末变化包括弥散性血管内凝血，伴有体温降低、白细胞和血小板计数减少，以及鲎试剂检测呈阳性。除血栓形成和出血外，在感染前给予环磷酰胺的小鼠中也发现了类似变化。结果表明，血管内凝血和免疫复合物形成均不是导致莱姆病死亡的主要因素。
