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光化学疗法对银屑病患者淋巴细胞的刺激作用。淋巴细胞转化的研究。

Stimulation of lymphocytes in patients with psoriasis under photochemotherapy. A study of lymphocyte transformation.

作者信息

Wassilew S W

出版信息

Arch Dermatol Res. 1978 Nov 10;263(2):127-34. doi: 10.1007/BF00446433.

Abstract

Lymphocyte-transformation by phytohaemagglutinine (PHA) was examined in 21 patients with generalized psoriasis during photochemotherapy (PUVA). Lymphocyte-transformation-tests (LTT) were performed before and after 8-methoxypsoralen (8-MOP) medication, before and after the initial irradiation and before and after the first maintenance irradiation four to six weeks later. Spontaneous and PHA-induced lymphocyte-transformation was not altered by 8-MOP alone or in combination with UVA irradiation.

摘要

在光化学疗法(PUVA)期间,对21例泛发性银屑病患者进行了植物血凝素(PHA)诱导的淋巴细胞转化检测。在服用8-甲氧基补骨脂素(8-MOP)之前和之后、初次照射之前和之后以及4至6周后的首次维持照射之前和之后,均进行了淋巴细胞转化试验(LTT)。单独使用8-MOP或与紫外线A(UVA)照射联合使用,均不会改变自发和PHA诱导的淋巴细胞转化。

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