DiZerega G S, Yonekura M L, Keegan K, Roy S, Nakamura R, Ledger W
Obstet Gynecol. 1980 May;55(5):587-90.
Presented are blood culture results obtained from 200 patients with post-cesarean section endomyometritis treated with either penicillin-gentamicin or clindamycin-gentamicin. Their clinical course is correlated to their blood culture results by the fever index. Fifty-three percent of the 60 organisms isolated from 48 patients were anaerobic bacteria. Patients from whose blood cultures anaerobic bacteria were recovered had higher fever indexes than did those with aerobic isolates (P less than .05). Clindamycin-gentamicin patients from whose blood cultures anaerobic organisms were isolated had less febrile morbidity than did comparable penicillin-gentamicin patients. Patients with Bacteroides fragilis bacteremia had the highest fever indexes overall. Therefore, patients with post-cesarean section endomyometritis have less febrile morbidity if they are initially treated with a drug effective against anaerobic bacteria, especially B fragilis.
本文呈现了200例剖宫产术后子宫内膜炎患者的血培养结果，这些患者分别接受青霉素-庆大霉素或克林霉素-庆大霉素治疗。通过发热指数将他们的临床病程与血培养结果相关联。从48例患者中分离出的60株微生物中，53%为厌氧菌。血培养中分离出厌氧菌的患者发热指数高于分离出需氧菌的患者（P<0.05）。血培养中分离出厌氧微生物的克林霉素-庆大霉素治疗患者发热发病率低于相应的青霉素-庆大霉素治疗患者。脆弱拟杆菌菌血症患者的发热指数总体最高。因此，剖宫产术后子宫内膜炎患者若初始接受对厌氧菌尤其是脆弱拟杆菌有效的药物治疗，发热发病率会更低。
