Diehl A K, Stern M P, Ostrower V S, Friedman P C
South Med J. 1980 Apr;73(4):438-41, 443. doi: 10.1097/00007611-198004000-00012.
Clinical observations have suggested that gallstones are increased in frequency in Mexican-Americans compared to other ethnic groups. Past autopsy surveys have demonstrated a low prevalence in blacks compared to whites. We retrospectively reviewed 1,018 charts to study the prevalence of cholelithiasis in ambulatory women of these three racial/ethnic backgrounds. Mexican-American women were found to have a prevalence of gallbladder disease approximately three times that of black women, with Anglo prevalences falling in an intermediate range. The prevalence of cholelithiasis was also positively associated with increasing age and diabetes, but not with serum cholesterol, use of oral contraceptives or conjugated estrogens, parity, hypertension, menstrual status, or smoking. An association with obesity was shown but could not be shown to be independent of other risk factors.
临床观察表明，与其他种族群体相比，墨西哥裔美国人胆结石的发病率更高。过去的尸检调查显示，黑人的患病率低于白人。我们回顾性地查阅了1018份病历，以研究这三种种族/族裔背景的门诊女性中胆石症的患病率。结果发现，墨西哥裔美国女性胆囊疾病的患病率约为黑人女性的三倍，英裔美国人的患病率处于中间范围。胆石症的患病率也与年龄增长和糖尿病呈正相关，但与血清胆固醇、口服避孕药或共轭雌激素的使用、产次、高血压、月经状况或吸烟无关。虽然显示出与肥胖有关，但无法证明其独立于其他风险因素。
