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对近交系大鼠品系进行电泳蛋白质多态性筛选。

Screening of inbred rat strains for electrophoretic protein polymorphisms.

作者信息

Bender K, Günther E

出版信息

Biochem Genet. 1978 Jun;16(5-6):387-98. doi: 10.1007/BF00484206.

Abstract

Nineteen inbred strains of the laboratory rat (Rattus norvegicus) were investigated for genetic differences by starch and agarose gel electrophoretic techniques. For six out of 21 loci, interstrain differences were observed: Tf, 6PGD, Es-1, Es-4, Es-5, and Svp. The variants are briefly described and the allelic distributions are tabulated. The 6GPD locus was found to be linked neither to the major histocompatibility gene region nor to the coat color genes c, a, h.

摘要

通过淀粉和琼脂糖凝胶电泳技术,对19个近交系实验大鼠(褐家鼠)进行了遗传差异研究。在21个基因座中的6个基因座上观察到了品系间差异:转铁蛋白(Tf)、6-磷酸葡萄糖脱氢酶(6PGD)、酯酶-1(Es-1)、酯酶-4(Es-4)、酯酶-5(Es-5)和血清维生素结合蛋白(Svp)。简要描述了这些变体,并列出了等位基因分布情况。发现6GPD基因座既不与主要组织相容性基因区域连锁,也不与毛色基因c、a、h连锁。

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