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对近交系大鼠品系进行电泳蛋白质多态性筛选。

Screening of inbred rat strains for electrophoretic protein polymorphisms.

作者信息

Bender K, Günther E

出版信息

Biochem Genet. 1978 Jun;16(5-6):387-98. doi: 10.1007/BF00484206.

DOI:10.1007/BF00484206
PMID:736880
Abstract

Nineteen inbred strains of the laboratory rat (Rattus norvegicus) were investigated for genetic differences by starch and agarose gel electrophoretic techniques. For six out of 21 loci, interstrain differences were observed: Tf, 6PGD, Es-1, Es-4, Es-5, and Svp. The variants are briefly described and the allelic distributions are tabulated. The 6GPD locus was found to be linked neither to the major histocompatibility gene region nor to the coat color genes c, a, h.

摘要

通过淀粉和琼脂糖凝胶电泳技术，对19个近交系实验大鼠（褐家鼠）进行了遗传差异研究。在21个基因座中的6个基因座上观察到了品系间差异：转铁蛋白（Tf）、6-磷酸葡萄糖脱氢酶（6PGD）、酯酶-1（Es-1）、酯酶-4（Es-4）、酯酶-5（Es-5）和血清维生素结合蛋白（Svp）。简要描述了这些变体，并列出了等位基因分布情况。发现6GPD基因座既不与主要组织相容性基因区域连锁，也不与毛色基因c、a、h连锁。

相似文献

1
Screening of inbred rat strains for electrophoretic protein polymorphisms.对近交系大鼠品系进行电泳蛋白质多态性筛选。
Biochem Genet. 1978 Jun;16(5-6):387-98. doi: 10.1007/BF00484206.
2
Biochemical polymorphism in the rat: genetics of three electrophoretic variants and characterization of inbred strains.大鼠的生化多态性：三种电泳变体的遗传学及近交系的特征分析
Biochem Genet. 1981 Feb;19(1-2):173-86. doi: 10.1007/BF00486146.
3
Enzyme markers in inbred rat strains: genetics of new markers and strain profiles.近交系大鼠品系中的酶标记：新标记的遗传学及品系概况
Biochem Genet. 1984 Aug;22(7-8):611-29. doi: 10.1007/BF00485848.
4
New polymorphisms of esterase 7 and esterase 8 in inbred strains of rats: tissue expression and linkage studies.大鼠近交系中酯酶7和酯酶8的新多态性：组织表达及连锁研究。
Biochem Genet. 1980 Oct;18(9-10):879-87. doi: 10.1007/BF00500121.
5
Peptidase-3 (Pep-3), dipeptidase variant in the rat homologous to mouse pep-3 (Dip-1) and human PEP-c.肽酶-3（Pep-3），大鼠体内的二肽酶变体，与小鼠肽酶-3（Dip-1）和人类PEP-c同源。
Biochem Genet. 1980 Oct;18(9-10):1019-26. doi: 10.1007/BF00500132.
6
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Jikken Dobutsu. 1987 Jul;36(3):267-72.
7
Assignment of the Es-6 locus to linkage group VII of the rat (Rattus norvegicus) by the use of HXB recombinant inbred rat strains.利用HXB重组近交系大鼠品系将Es-6基因座定位于大鼠（褐家鼠）的第七连锁群。
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Lab Anim. 1985 Jul;19(3):169-72. doi: 10.1258/002367785780893502.
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Electrophoretic protein variants in inbred strains of Rattus norvegicus: strain distribution, description of a new esterase polymorphism, and linkage studies.褐家鼠近交系中的电泳蛋白质变体：品系分布、一种新的酯酶多态性描述及连锁研究。
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10
Hemoglobin polymorphism in inbred strains of rats (Rattus norvegicus).大鼠（褐家鼠）近交系中的血红蛋白多态性。
Biochem Genet. 1982 Apr;20(3-4):395-403. doi: 10.1007/BF00484433.

引用本文的文献

1
Biochemical polymorphism in the rat: genetics of three electrophoretic variants and characterization of inbred strains.大鼠的生化多态性：三种电泳变体的遗传学及近交系的特征分析
Biochem Genet. 1981 Feb;19(1-2):173-86. doi: 10.1007/BF00486146.
2
New polymorphisms of esterase 7 and esterase 8 in inbred strains of rats: tissue expression and linkage studies.大鼠近交系中酯酶7和酯酶8的新多态性：组织表达及连锁研究。
Biochem Genet. 1980 Oct;18(9-10):879-87. doi: 10.1007/BF00500121.
3
Es-6, a further polymorphic esterase in the rat.Es-6，大鼠体内的另一种多态性酯酶。

本文引用的文献

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A genetically controlled esterase in rat plasma.大鼠血浆中一种受基因控制的酯酶。
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10
Nonspecific esterases of mammalian testis. Comparative studies on the mouse (Mus musculus) and rat (rattus norvegicus).哺乳动物睾丸的非特异性酯酶。小鼠（小家鼠）和大鼠（褐家鼠）的比较研究。
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Vox Sang. 1970 Jul;19(1):47-56. doi: 10.1111/j.1423-0410.1970.tb01494.x.
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Zymogram analyses of various organs from spontaneously hypertensive rats. A genetico-biochemical study.自发性高血压大鼠各器官的酶谱分析。一项遗传生化研究。
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Phosphogluconate dehydrogenase polymorphism in British wild rats.
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A histocompatible chromosome marker system in the laboratory rat Rattus norvegicus.实验大鼠褐家鼠中的一种组织相容性染色体标记系统。
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