Ebbesen F, Edelsten D, Hertel J
Acta Paediatr Scand. 1980 Jan;69(1):65-8. doi: 10.1111/j.1651-2227.1980.tb07031.x.
Sixty newborn infants with normal birth weight suffering from uncomplicated hyperbilirubinemia were studied. They were fed human mature milk from which lactose had been eliminated, whereafter either sucrose ("sucrose milk") or lactose ("lactose milk") was added. 30 infants received ordinary phototherapy and 30 intensive phototherapy (blue double light). 15 in each group had "sucrose milk" and 15 "lactose milk". There was no significant difference between the increase in blood glucose (delta BS) by lactose tolerance tests performed before phototherapy (LTT1) and by those performed during phototherapy (LTT11), neither in infants treated with ordinary nor with intensive phototherapy. All infants had normal delta BS-LTT11, except one receiving ordinary phototherapy. There was no significant difference in gut transit time between infants having "sucrose milk" and infants having "lactose milk", neither in those treated with ordinary nor with intensive phototherapy. Gut transit time was significantly shorter in infants treated with intensive phototherapy than in infants treated with ordinary phototherapy without there being any significant difference in delta BS-LTT11. The infant with flat LTT11 may have developed lactose malabsorption during the phototherapy. Thus, lactose malabsorption is not the usual cause of the reduced gut transit time during phototherapy and must be a rare complication in phototherapy.
对60名出生体重正常、患有单纯性高胆红素血症的新生儿进行了研究。他们被喂食去除乳糖后的人成熟乳，然后添加蔗糖（“蔗糖奶”）或乳糖（“乳糖奶”）。30名婴儿接受普通光疗，30名接受强化光疗（蓝光双光）。每组15名婴儿喝“蔗糖奶”，15名喝“乳糖奶”。在光疗前进行的乳糖耐量试验（LTT1）和光疗期间进行的乳糖耐量试验（LTT11）中，普通光疗组和强化光疗组婴儿的血糖升高幅度（δBS）均无显著差异。除一名接受普通光疗的婴儿外，所有婴儿的δBS-LTT11均正常。喝“蔗糖奶”的婴儿和喝“乳糖奶”的婴儿在肠道转运时间上没有显著差异，无论是普通光疗组还是强化光疗组。强化光疗组婴儿的肠道转运时间明显短于普通光疗组婴儿，而δBS-LTT11没有显著差异。LTT11结果平平的婴儿可能在光疗期间出现了乳糖吸收不良。因此，乳糖吸收不良不是光疗期间肠道转运时间缩短的常见原因，而且一定是光疗中罕见的并发症。
