Makukho L V, Volkolupova O P, Gauze G F
Antibiotiki. 1980 Apr;25(4):294-6.
Amphotericin B has a significant cytostatic effect on lymphadenosis cells of mice NK/LY. In a concentration of 6 units/ml it inhibits an increase in total nucleic acids by 50 per cent. Such cytostatic effect of amphotericin B combines with the effect of carminomycin and adriamycin. In concentrations having no cytostatic effect amphotericin B does not enhance the action of adriamycin and carminomycin on tumor cells.
两性霉素B对小鼠NK/LY淋巴结病细胞具有显著的细胞生长抑制作用。在浓度为6单位/毫升时,它能抑制总核酸增加50%。两性霉素B的这种细胞生长抑制作用与洋红霉素和阿霉素的作用相结合。在没有细胞生长抑制作用的浓度下,两性霉素B不会增强阿霉素和洋红霉素对肿瘤细胞的作用。