Girolami A, Dal Bo Zanon R, De Marco L, Cappellato G
Blut. 1980 Apr;40(4):267-73. doi: 10.1007/BF01080186.
Factor VII activity and cross-reacting material was assayed in fresh and deep frozen non-contacted plasma in 43 patients with Hemophilia B belonging to different kindreds. Factor VII activity was found to be slightly decreased (about of 50% normal) in 12 patients, regardless of the thromboplastin used. In an additional patient (hemophilia BM) factor VII was slightly decreased in 1 : 10 diluted plasma but was normal in further diluted plasma. In the remaining 30 patients factor VII activity was normal. No significant variation was found between fresh and deep frozen plasmas. Factor VII antigen or cross-reacting material was normal.
对43例来自不同家族的B型血友病患者的新鲜和深冻未接触血浆进行了因子VII活性和交叉反应物质检测。发现12例患者的因子VII活性略有降低（约为正常水平的50%），与所使用的凝血活酶无关。另有1例患者（BM型血友病），在1:10稀释血浆中因子VII略有降低，但在进一步稀释的血浆中则正常。其余30例患者的因子VII活性正常。新鲜血浆和深冻血浆之间未发现显著差异。因子VII抗原或交叉反应物质正常。
